Ovarian platelet-rich plasma (PRP) therapy is a medical procedure that involves injecting a patient’s own platelet-rich plasma into the ovaries to improve fertility. PRP is derived from the patient’s own blood and contains growth factors that can stimulate ovarian function and increase the chances of pregnancy . PRP therapy has been used as an adjunct to fertility treatments in women with very low ovarian reserve and premature ovarian insufficiency. Recent literature in both humans and animals suggest that intraovarian PRP administration in the setting of poor ovarian reserve may help ovarian function and increase the chances of pregnancy. The effectiveness of PRP therapy for ovarian rejuvenation varies depending on factors such as age and the number of eggs frozen.