Sperm Function Test

At Eva IVF & Women’s Centre, we believe that assessing male fertility is about more than just counting sperm. While a standard semen analysis gives basic information about sperm quantity and movement, it doesn’t tell us how well the sperm can actually do their job — fertilize an egg. That’s where Sperm Function Tests come in.
These advanced diagnostics offer a deeper, more accurate evaluation of sperm performance, helping us identify hidden causes of infertility and select the most effective fertility treatments tailored for each couple.

What Are Sperm Function Tests?

Sperm function tests are a group of advanced laboratory evaluations designed to assess the biological capabilities of sperm — how well they survive, swim, bind to the egg, and undergo necessary physiological changes for fertilization.
These tests go beyond basic parameters like count and motility to evaluate:
     • Sperm DNA integrity
     • Membrane integrity
     • Reactive oxygen species (ROS) levels
     • Acrosome reaction capacity

What Are Sperm Function Tests?

💡 Even if standard semen analysis appears normal, sperm function abnormalities can prevent successful conception or cause repeated IVF failure.

Who Should Undergo Sperm Function Testing?

These tests are especially recommended for:
✔ Couples with unexplained infertility
✔ Men with normal semen reports but no pregnancy after months of trying
✔ Repeated IUI or IVF failure
✔ History of miscarriage or poor embryo development
✔ Men exposed to toxins, heat, radiation, or long-term medications

💡 Identifying functional issues early can save time, money, and emotional stress in your fertility journey.

Key Sperm Function Tests We Offer at Eva IVF

1. Sperm DNA Fragmentation Test
Evaluates the quality and stability of genetic material within the sperm cell.
✅ High fragmentation may lead to failed fertilization, poor embryo quality, or miscarriage.
🔬 We use the SCSA, TUNEL, or COMET assays based on clinical indication.
2. Reactive Oxygen Species (ROS) Testing
Measures oxidative stress in semen.
✅ Excess ROS can damage sperm DNA and reduce motility.
💡 Ideal for men with varicocele, smoking, diabetes, or stress.
3. Hypo-Osmotic Swelling (HOS) Test
Checks the integrity of the sperm membrane.
✅ Sperm with intact membranes swell in hypo-osmotic solutions, indicating viability.
4. Acrosome Reaction Test
Evaluates the sperm’s ability to undergo the acrosome reaction, a key process required to penetrate the egg’s outer layer.
✅ A failed reaction can prevent fertilization despite normal sperm appearance.
5. Sperm Chromatin Structure Assay (SCSA)
Analyzes the structure and packaging of DNA within sperm cells.
✅ Poor chromatin compaction may lead to embryo arrest or IVF failure.

Step-by-Step: How the Testing Process Works

1. Consultation & Evaluation
• You meet with our fertility and andrology team
• Medical history, lifestyle factors, and prior test results are reviewed
• A personalized diagnostic plan is created based on your fertility goals
2. Sample Collection
• A semen sample is collected via masturbation after 2–5 days of abstinence
• Collection is done in a private, comfortable room within our centre
• In certain cases, home collection kits may be provided (for nearby patients)
3. Laboratory Testing
• Our embryologists and lab specialists run advanced tests using cutting-edge equipment
• Tests are performed on the same day to ensure accuracy and viability
4. Results Review & Treatment Planning
• Your fertility specialist explains each result in detail
• Based on findings, options such as lifestyle changes, antioxidants, ICSI, PICSI, or surgical sperm retrieval may be discussed
• You and your partner receive a complete roadmap for conception success

Common Misconceptions About Sperm Testing

❌ My sperm count is normal, so everything is fine
➡️ DNA damage or membrane issues can still affect fertility despite a good count.
❌ Only women need detailed fertility testing
➡️ Male factors contribute to nearly 50% of infertility cases.
❌ There’s nothing I can do if results are bad
➡️ Treatments like antioxidants, sperm selection techniques, or surgical retrieval can dramatically improve outcomes.

Why Choose Eva IVF for Sperm Function Testing?

why eva

🌟 Specialized Male Fertility Laboratory – Equipped for advanced andrology diagnostics
🌟 Experienced Team of Andrologists and Embryologists
🌟 Fertility-Focused Analysis – We interpret results in the context of your conception plan
🌟 Immediate Integration with Treatment Options (IUI, IVF, ICSI)
🌟 Transparent Reporting and One-on-One Counseling
🌟 Supportive, Confidential, and Non-Judgmental Environment

At Eva IVF, we look beyond the basics — because every couple deserves to know the full picture.



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